Vitamin B3 (Niacin) Interactions
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The following are the medications and supplements that are more likely to cause a reaction with vitamin B3 (niacin) supplements:
- Antibiotics
People taking antibiotics may have reduced absorption and effectiveness of vitamin B3 (niacin) from the foods they eat, so could need supplementation if they are on the antibiotics long term. People taking antibiotics should seek the advice of their doctor about vitamin B3 (niacin) supplements before taking them. - Antidiabetics
People that are taking antidiabetic medications should not take vitamin B3 (niacin) supplements, especially at high levels, because the vitamin B3 (niacin) reduces the effectiveness of the antidiabetic medications, somewhat inactivating their effect. - Beta-andrenergic blockers
People that are taking beta-andrenergic blockers should definitely not take vitamin B3 (niacin) supplements, especially at high levels, because this combination lowers blood pressure to extremely low levels, which could be dangerous. - Chenodiol
People that are taking chenodiol should avoid taking vitamin B3 (niacin) supplements as they can reduce the effectiveness of the Chenodiol medication, somewhat inactivating its effect. - Guanethidine
People that are taking guanethidine should avoid taking vitamin B3 (niacin) supplements because they can increase the effect of the Guanethidine, which could be dangerous if high levels are taken.
Vitamin B3 (niacin) has interactions with numerous medications and supplements
- HMG-CoA reductase inhibitors
People that are taking HMG-CoA reductase inhibitors could experience a rapid breakdown of their muscles and kidney failure if they also take vitamin B3 (niacin) supplements at the same time. People taking HMG-CoA reductase inhibitors should not take vitamin B3 (niacin) supplements at all. - Isoniazid
People that are taking isoniazid may experience a reduction in the effectiveness of vitamin B3 (niacin) if they are taken at the same time. Always take the vitamin B3 (niacin) supplements at least 2 hours before or after taking the Isoniazid. - Mecanylamine
People that are taking mecanylamine should definitely not take vitamin B3 (niacin) supplements, especially at high levels, because this combination lowers blood pressure to extremely low levels, which could be dangerous. - Parglyine
People that are taking parglyine should definitely not take vitamin B3 (niacin) supplements, especially at high levels, because this combination lowers blood pressure to extremely low levels, which could be dangerous. - Ursodiol
People that are taking ursodiol should not take vitamin B3 (niacin) supplements at the same time, as the vitamin B3 (niacin) can cause a reduction in the effectiveness of the Ursodiol medication, somewhat inactivating its effect.