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Vitamin K Cautions

Certain people should not take vitamin K supplements at all:

  • People with a G6PD deficiency (a metabolic disorder)
  • People with liver disease

Other people should seek medical advice before taking vitamin K supplements:

  • People that are about to have surgery
  • People that are about to have dental treatment
  • People taking any medications
  • People with cystic fibrosis
  • People with severe diarrhoea that occurs for a long time
  • People with severe gastrointestinal problems
  • Women that are pregnant or breastfeeding
Certain people should not take vitamin K supplements, while other groups of people should seek medical advice about supplementation

Toxic Levels of Vitamin K

Vitamin K can be toxic at doses greater than 100mcg per day when the synthetic form of vitamin K is taken K3 - menadione.

Overdosage and Toxicity Symptoms

Toxicity of the synthetic form of vitamin K, K3 - menadione can cause the following toxicity symptoms:

  • Anaemia
  • Flushing
  • Gastrointestinal pains
  • Impaired liver function
  • Itchy skin* (seek emergency treatment for this symptom)
  • Jaundice
  • Redness, pain or swelling at injection point
  • Sweating

People experiencing any of the above toxicity symptoms should discontinue their vitamin K supplements and seek medical advice.

Overdosage and toxicity is more likely to occur from taking too many supplements, whereas dietary intake of vitamin K is highly unlikely to cause overdosage.

When infants and newborns are given too much vitamin K, it could present with the following toxicity symptoms:

  • Haemolytic anaemia
  • Hyperbilirubin (high amounts of bilirubin in the blood)

If either of these two symptoms above occur in newborns or infants, seek immediate emergency treatment.

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