Vitamin B2 (Riboflavin) Interactions

The following are the medications and supplements that are more likely to cause a reaction with vitamin B2 (riboflavin) supplements:

Antidepressants (tricyclic)
Tricyclic antidepressants may reduce the effectiveness of vitamin B2 (riboflavin), so could cause a deficiency in people taking these types of antidepressants over the longer term and supplementation may be required.
Chloropromazine
People taking chloropromazine, an anti-psychotic medication, may have reduced absorption or effectiveness of the vitamin B2 (riboflavin) in foods that are eaten or alter the intended effect of riboflavin supplementation. People taking this medication need to seek advice from their doctor about vitamin B2 (riboflavin) supplementation.
Copper
People taking high levels of copper supplements can reduce the absorption and effectiveness of vitamin B2 (riboflavin) in foods that are eaten and this could create a deficiency and supplementation may be required.
Iron
Iron supplements have a synergistic effect on vitamin B2 (riboflavin) supplements, both the vitamin B2 (riboflavin) and iron are absorbed much better and are more effective when they are taken together.
MAO inhibitors (phenelzine)
People taking MAO inhibitors (such as phenelzine) may have reduced absorption or effectiveness of the vitamin B2 (riboflavin) in foods that are eaten or alter the intended effect of riboflavin supplementation. People taking this medication need to seek advice from their doctor about vitamin B2 (riboflavin) supplementation.

Vitamin B2 (riboflavin) has interactions with a number of medications and supplements

Methotrexate
People taking methotrexate, an anti-cancer medication, may have reduced absorption or effectiveness of the vitamin B2 (riboflavin) in foods that are eaten or alter the intended effect of riboflavin supplementation. People taking this medication need to seek advice from their doctor about vitamin B2 (riboflavin) supplementation.
Oral contraceptives
Women taking oral contraceptives may have reduced absorption or effectiveness of the vitamin B2 (riboflavin) in foods that are eaten.
Phenothiazines
Phenothiazines may reduce the effectiveness of vitamin B2 (riboflavin), so could cause a deficiency in people taking phenothiazines, especially over the longer term and supplementation may be required.
Probenecid
Probenecid may reduce the effectiveness of vitamin B2 (riboflavin), so could cause a deficiency in people taking probencid, especially over the longer term and supplementation may be required.

24 June 2013