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Vitamin B12 (Cobalamin) Cautions

While vitamin B12 (cobalamin) is a very non-toxic vitamin, there are some people who should not take it:

  • People with Leber's disease
    People with Leber's disease may experience severe and rapid onset of optic atrophy if they take vitamin B12 (cobalamin) supplements.

Overdosage and Toxicity Symptoms

There are no overdosage or toxicity symptoms, other than really high levels of red blood cells if dosage of vitamin B12 (cobalamin) is extremely high, but this is only temporary - once supplementation stops blood levels return to normal.

The only other toxicity symptom (which is very rare but can be life-threatening) is:

  • Itchy skin after intravenous vitamin B12 (cobalamin)

This symptom requires emergency treatment as it could signify a dangerous allergic reaction to the vitamin B12 (cobalamin) injection.

While vitamin B12 (cobalamin) is a very non-toxic vitamin, there are some people who should not take it

Toxic Levels of vitamin B12 (cobalamin)

Vitamin B12 (cobalamin) is not very toxic even with really high supplementation (when doses are higher than 1000mcg per day).

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